Nolgripp Ultra Tablets

Nol gripp ultra

COMPOSITION:
Each uncoated tablet contains:
Paracetamol BP 500 mg
Phenylepherine HCL BP 10 mg
Chlorpheniramine Maleate BP 2 mg
Colour: Quinoline Yellow

INDICATIONS:
Nolgripp Ultra is indicated for Fever, Cold, Flu, Body ache, Allergic Rhinitis, Nasal Congestion, Runny nose, Sneezing due to cold, Influenza, Sinusitis and Headache.

CONTRAINDICATIONS:
Nolgripp Ultra is contraindicated in conditions of Liver dysfunction, Renal failure and in patients with known hypersensitivity to Phenylephrine Hydrochloride, Chlorpheniramine Maleate and Paracetamol.

DESCRIPTION:
Nolgripp Ultra is a combination of pain reliever, anti-pyretic, anti-histamine, a cough suppressant and a decongestant. Paracetamol blocks the effect of endogenous pyrogen on the hypothalamic heat-regulating center by inhibiting prostaglandin synthesis. It is rapidly and completely absorbed with peak plasma concentration occurring in 10 to 60 minutes after oral administration. Phenylephrine Hydrochloride is a decongestant which relieves congestion and helps to breathe more easily. Oral absorption of Phenylephrine Hydrochloride is 73%. Presystemic metabolism is 60% and plasma half life is 2-3 hr. Chlorpheniramine Maleate is a H1 receptor antagonist which inhibits effects of histamine on smooth muscles, especially the constriction of respiratory smooth muscle and reduces the allergic component of infectious disease. Chlorpheniramine Maleate is absorbed from GI tract, with peak plasma concentration occurring in 2.5 hours after oral administration and distributed in all tissues of body. The plasma half life of Chlorpheniramine Maleate is 4 hours.

CONTRAINDICATIONS:
Nolgripp Ultra is contraindicated in conditions of Liver dysfunction, Renal failure and in patients with known hypersensitivity to Phenylephrine Hydrochloride, Chlorpheniramine Maleate and Paracetamol.

SIDE EFFECTS:
Gastrointestinal disturbances, Hepatotoxicity, Peptic ulcer, Prostatic hyperplasia, Hypertension, Drowsiness and Palpitation may occur. Symptoms of side effects, if any, should subside after discontinuing the medicine. If symptoms persist, please consult the physician.

DOSAGE:
Adults & Children above 12 years: 1 tablet 3-4 times a day.
Children 6 -12 years: ½ tablet 3-4 times a day.
Children below 6 years: As directed by the physician.

OVERDOSE: Overdose of Nolgripp Ultra can result in severe liver damage and sometimes acute renal tubular necrosis. Prompt treatment with Acetylcysteine or Methionine is essential. An appropriate method of gastric emptying may be used such as prompt emesis, activated charcoal (60 to 100 g in adults, 1 to 2 g/kg in children) or osmotic cathartic

STORAGE CONDITIONS:
Store in a cool, dark & dry place. Keep out of reach of children.

PRESENTATION:
4 Tablets packed in a blister and such 25 blisters packed in a duplex board carton with insert.